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EO 14363

Launching the Genesis Mission

ActiveSigned November 24, 2025
TechGovernmental – Public Policy and Government AffairsGovernmental – National SecurityIntellectual PropertyPrivacy and CybersecurityAI, Robotics and QuantumEnergy and InfrastructureDigital InfrastructureLife SciencesAerospace, Defense & Government Services

Summary

This EO establishes the “Genesis Mission,” a national initiative led by the Department of Energy to accelerate scientific discovery and technological innovation through an integrated AI platform that leverages federal research resources, datasets, and partnerships, aiming to advance key science and technology challenges, strengthen national security, and maintain U.S. global leadership in AI.

Agencies Impacted

  • DOE

Timeline

Immediate, 60, 90, 120, 240, 270.

Deliverable

Identify and submit to the APST a detailed list of at least 20 science and technology challenges (60 days); Identify Federal computing, storage, and networking resources available to support the Mission (90 days); (i) Identify initial data and model assets for use in the Mission (ii) Develop a plan for incorporating datasets with risk-based cybersecurity measures (120 days); Review capabilities for robotic laboratories and production facilities for AI-directed experimentation and manufacturing (240 days); Demonstrate initial operating capability of the Platform for at least one national challenge (270 days); Review and coordinate the development of an expanded list of science and technology challenges (30 days after submission of list).

Legal Challenges

No known legal challenges.