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EO 14297

Delivering Most-Favored-Nation Prescription Drug Pricing to American Patients

ActiveSigned May 12, 2025
Health and Life SciencesAntitrust and CompetitionGovernmental – Life Sciences / FDAGlobal ReachLife SciencesHealthcare

Summary

This Executive Order seeks to align U.S. prescription drug prices with those in comparably developed countries by implementing a “most-favored-nation” pricing strategy. It directs the Secretary of Health and Human Services to communicate price targets to pharmaceutical manufacturers within 30 days and to facilitate direct-to-consumer programs offering drugs at the most-favored-nation price. If significant progress is not made, the order authorizes additional actions, including proposed rulemaking, importation certifications, antitrust enforcement, export controls, and potential FDA regulatory reviews. The order also calls on the Department of Commerce and USTR to address international pricing practices that contribute to disproportionately high drug costs for American consumers.

Agencies Impacted

  • HHS
  • DOC
  • USTR

Timeline

30 days.

Deliverable

Communicate most-favored-nation price targets to pharmaceutical manufacturers — within 30 days

Legal Challenges

No known legal challenges.